PCR method of mycoplasma. Mycoplasmosis and ureaplasmosis: What is needed for an accurate diagnosis? Analyzes on mycoplasmosis and ureaplasm: where to pass and get results

And mycoplasma is not absolute pathogens, and their detection in analyzes does not require treatment, but not only in the case of pregnancy planning. When planning, everything is very difficult: (doctors themselves cannot agree on the need to treat these pathogens.

Therefore, the question of the need the treatment of ureaplasma and mycoplasma should be discussed with a personal doctor who deserves confidence.

Our personal opinion is that it's not correct to "treat analyzes". And you should not drink antibiotics, subject to the absence of complaints from a woman, with a normal smear on the flora and with the complete absence of clinical symptoms.

Ureaplasma and mycoplasma do not have clinical significance in obstetrics and gynecology. This is the pathogens of non-specific urethritis, more often in men. In 30% of cases and more - representatives of the normal microflora of sex tract. The detection of their PCR method is not an indication to their targeted treatment, even if there are symptoms of the inflammatory process - it is necessary to treat more frequent pathogens, and since they are chlamydia, and drugs used against them and urea- and mycoplasmas are the same, then The question of the treatment of Miko and Ureaplasmosis is removed. Even if we accept that they are and matter, they are still treated with the same drugs, therefore it does not make sense to determine.

Is it necessary to hand over sowing on mycoplasma and ureaplasma

The diagnosis of Mico- and ureaplasmosis is not needed. It is not necessary to take the tests on them - no blood on antibodies, nor sowing (especially since it really does it in single metropolitan laboratories, and the definition of sensitivity to antibiotics is technically uniformly, in conventional places they write the results of PCR as sowing), nor PCR.

If for some reason the analysis is made, it is not necessary to pay attention to its results, it is not a criterion for the formulation of the diagnosis, neither more appointment of treatment.

Pregnancy planning and pregnancy itself - not an indication for PCR diagnostics in general, and even more so for PCR diagnostics urea- and mycoplasmas. The maintenance in this case does not differ from the maintenance of non-empty women - complaints and smears.

Do not treat tests, but complaints. If there is no complaints, and the usual smear on the flora shows the normal number of leukocytes, no further examination and treatment is necessary. If the additional survey is still done, and something is found in PCR, this is not a criterion for treating treatment. In addition to the lack of clinical significance, ure- and mycoplasmas, it is necessary to remember the high frequency of false positive results of PCR. Assign this analysis in the absence of complaints in general, and in the presence of complaints - before or instead of a smear - incompetence and divorce for money.

If there is a complaint, and the smear made in a good laboratory, good, testimony for antibiotics is not, it is necessary to look for other causes of complaints - dysbacteriosis, concomitant diseases, hormonal imbalances, allergies, papillomatosis.

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If there are complaints and signs of the inflammatory process in the urinary system, antibiotic therapy is appointed - either according to the results of additional surveys (PCR and sowing with the definition of sensitivity) - on various pathogens (chlamydia, gonococci, trichomonas, streptococci, intestinal wand, etc. and TP), but not At urea- and mycoplasma, or "blindly" - against the main pathogens of such diseases (Gonokokkov and Chlamydia). The antihahlamicid drug is assigned necessarily, in any case, regardless of the results of the tests, since this is the most frequent pathogen, and since it does not have resistance to anti-flame retardant antibiotics (sowing with the definition of the sensitivity of chlamydia - also profanation). All Mico- and ureaplasma are sensitive to antihahlaidic drugs (an exception is some share of ureaplasm resistant to doxycycline). Therefore, even if, after some time, the pathogenicity and the clinical role of these microorganisms will prove, there is still an adequate treatment of inflammatory diseases without determination eliminates them together with chlamydia. Therefore, again - there is no point in determining them. Contrary to what they say now in many commercial centers, treatment in this case does not depend on the results of the analyzes, the scheme is one.

This scheme is very simple and inexpensive, a multicomponent list of antibiotics on two sheets against positive PCR on ureaplasma is incompetence and divorce for money. Doxycycline is an old drug, but the main pathogens of inflammatory diseases in gynecology have retained sensitivity to it. However, the duration of treatment is not shorter than 10 days. Equivalent in efficiency against the main pathogens is one-time reception 1 g of Sumameda. For those who continue to be afraid of ureaplasm, it is a drug of choice, since those ureaplasms that are genetically insensitive to doxycycline are sensitive to Sumamian. Scientific research has proven the equivalence of exchange rate treatment to a single reception of 1 g. Quickly, simply, cheap.

Malaya MM gynecologist

Mycoplasmosis and ureaplasmosis

On the question of the clinical significance of genital mycoplasmas, it is difficult to give an unambiguous answer, at least at the moment. The fact is that research of their etiological role with various pathological conditions of both female and male urogenital systems began relatively recently.

If there is a clinic of cervicitis and / or urethritis in women or urethritis in men, then at the initial stage economically not advisable examination for genital mycoplasmas. Even if the gonococci and chlamydia did not find available methods in these diseases, then they need to be treated anyway. It is recommended to prescribe an antihionococcal preparation (once ceftriaxone or ciprofloxacin) in combination with anti-flame retardant (once-azithromycin or a 7-day course of other drugs). If treatment is ineffective, then a re-examination of culture methods for gonor and chlamydia is necessary. When detecting gonducts - re-treatment after determining the sensitivity or if it is impossible to determine its determination from another group. Chlamydium has not yet been identified by clinically significant resistance to specific preparations (tetracycles, erythromycin, azithromycin).

Anti-flame preparations are effective and in relation to genital mycoplasmas in the same doses. Tetracyclines operate on Miko and at ureaplasma. However, recently it has been established that about 10% ureaplasm is resistant to tetracycles, therefore, in the ineffectiveness of the treatment of urethritis using doxycycline, erythromycin or azithromycin or offlossacin is necessary.

The type of ureaplasma urealyticum consists of 14 or more serovars, which are divided into 2 bivear. Previously, they were called Biovar 1 or Parvo and Biovar 1 or T960. Currently, these bows are regarded as 2 various views: U.Parvum and U.Urealyticum, respectively. They differ in prevalence. U.Parvum is found in 81-90%, U.Urealyticum in 7-30% of women, and sometimes they are combined - 3-6% of cases. View U.Urealyticum, i.e. Former Biovar 2 (T960) prevails in women with inflammatory diseases of the small pelvis organs, complications of pregnancy, and is also more likely to be resistant to tetracyclines. The definition of these biovars is carried out in research purposes and is not necessary and economically appropriate in routine clinical practice.

Pregnant There should be a survey for gonorrhea, genital chlamydia, trichomoniasis, bacterial vaginosis and when identifying - to obtain antibacterial therapy. There is no reason for a targeted examination of them on genital mycoplasmas and the eradication of these microorganisms. It should not be routine to prescribe antibiotics to prolong pregnancy in the threat of its interrupt, except when identifying gonorrhea, trichomoniasis or bacterial vaginosis.

S.V. SEXIN, NII antimicrobial chemotherapy

Ureaplasma and mycoplasma. Questions and Answers / H2\u003e

What is ureaplasma and mycoplasma?

• Mycoplasma pneumonia (Mycoplasma Pneumoniae), inhabitants in the rotoglot and upper respiratory tract of man
• and three genital (genital) mycoplasmas living in the urinary system: human mycoplasma (Mycoplasma hominis)
• Ureaplasm (Ureaplasma Species), which is divided into 2 subspecies (Ureaplasma Urealyticum and Ureaplasma Parvum)
• Genital Mycoplasma (Mycoplasma Genitalium)

Recently, pathogenicity (harmfulness for the body) has been discovered (harmfulness) still in two mycoplasmas found in humans. it

• Enzymatic mycoplasma (Mycoplasma Fermentans) found in the Rothoglotka
• Penetrating mycoplasma (Mycoplasma Penetrans), inhabitants in the human urinary system.

How often are mycoplasm in humans?

Ureaplasm (Ureaplasma Sp.), It is detected in 40-80% of sexually active women who do not complaints. In men, the frequency of detection of ureaplasm is less and is 15-20%. About 20% of newborns are infected with ureaplasms.
Human mycoplasma (Mycoplasma Hominis) is detected in 21-53% of sexually active women and in 2-5% of men.
About 5% of children older than 3 months and 10% adults who do not lead sexual life are infected with genital (sex) mycoplasmas

How can I get sick by mycoplasmas?

Genital mycoplasmas (M. Hominis, m. Genitalium, ureaplasma sp., M.penetrans) can be infected only in three ways:

• with sexual contact (including orally genital contact)
• when transferring an infection from a mother to the fetus through an infected placenta or during childbirth
• when transplantation (transplant) of organs

Respiratory mycoplasmas (M.Pneumoniae, M.Fermentans) are transmitted by air-droplet. Genital mycoplasmas cannot be infected when visiting pools, toilets and through bedding.

What diseases can cause mycoplasm?

Mycoplasma often find healthy people. The reasons why mycoplasmas cause diseases in part of the people they are fully unknown are completely infected. Naturally, the most often mycoplasma causes diseases in individuals with immunodeficiency caused by HIV infection and under hypogammaglobulinemia (reducing the number of certain antibodies), but often mycoplasma cause diseases and in people who do not have immunodeficiency and with a normal level of antibodies.

In women, mycoplasma can cause the following diseases:

• Cervicitis (inflammation of the cervical cervix) in women are caused by genital mycoplasma (Mycoplasma genitalium)
• Vaginite (inflammation of the vagina) - there are no proven facts that genital myoplasms cause vaginitis, but ureaplasma and M.Hominis often find in women with bacterial vaginosis
• Inflammatory diseases of the small pelvis (wave) in women - 10% of women with Salpingitis revealed M.Hominis, there is also data on a possible role in the development of Ureaplasma Sp. and M. Genitalium.
• Postpartum and post-fever - Approximately 10% of sick women are determined by M.Hominis and (or) ureaplasma sp.
• Pelonephritis - 5% of women with pyelonephritis caused the cause of the disease is M.Hominis
• A sharp urethral syndrome (frequent and uncontrollable urination) in women are often associated with Ureaplasma sp.

In pregnant women, mycoplasma can lead to the following consequences: it is possible to infect the placenta, which leads to premature interruption of pregnancy, premature childbirth and the birth of newborns with low weight.

In both floors, mycoplasmosis can lead to sexually related reactive arthritis (joint damage), which are called by M. Fermentans, M. Hominis and Ureaplasma sp.

There is data on the possible causal role M. Hominis and Ureaplasma sp. In the development of subcutaneous abcesses and octiomyelitis.
Some studies show the relationship between the infection by ureaplasm and the development of urolithiasis.

Mycoplasma in newborns

Of particular danger are diseases caused by mycoplasmas in newborns. The infection of the newborn occurs or in intrauterine infection during pregnancy or during childbirth.

With genital micapoplasmas in newborns associated:

• Acute pneumonia (lung inflammation) newborn
• Chronic lung disease
• Bronchopulmonary dysplasia (underdevelopment)
• Bathremia and sepsis (blood infection)
• (inflammation of brain shells)

How do diseases associated with genital mycoplasmas diagnose?

In the presence of a disease, which can be caused by genital mycoplasmas, conduct a culture study (bacteriological sowing on mycoplasm) and the study by the PCR method.
The determination of the presence and amount of antibodies in the blood for diagnostics is not applicable.

How are diseases associated with genital mycoplasmas be treated?

For the treatment of diseases associated with mycoplasmas, various antibiotics apply. Tetracyclines (doxycycline), macrolides (erythromycin, clarithromycin), azalida (azithromycin), fluoroquinolones (ofloxacin, levofloxacin, moxifloxacin) are used most often. Need to take into account that different types Mycoplasmas have different sensitivity to various groups of antibiotics.
The effectiveness of the use of drugs affecting immunity, enzymes, vitamins, local and physiotherapeutic treatment in the treatment of diseases caused by mycoplasmas is not proved and does not apply in developed countries of the world.

How can I be protected from infection with genital mycoplasmas?

If you are not infected with mycoplasmas, then you need to take certain measures to prevent infection. Most effective method Prevention is the use of a condom.

My PCR method revealed ureaplasm (mycoplasma), but I do not have any signs of the disease. Do I need treatment of ureaplasma (mycoplasm) before conception?

If your sexual partner has no signs of the disease caused by mycoplasmas and (or) you are not going to change it and (or) do not plan for pregnancy in the near future, treatment is not appointed.

I am pregnant and I have detected ureaplasm (mycoplasma). Do I need to treat ureaplasma during pregnancy?

Numerous studies are shown that during pregnancy, intrauterine infection and placement of the placenta may occur, which can lead to premature childbirth and the birth of newborns with low weight, as well as their infection and the development of bronchopulmonary diseases and other complications. In this way, many doctors prescribe treatment in these Cases.

I revealed a disease associated with ureaplasm (mycoplasmas), and my sexual partner has no signs of the disease and the pathogen detected from me is not determined. Does my partner need to be treated from ureaplasma?

There is no need. Some doctors in such cases recommends a re-examination of sexual partners after a certain period of time (from 2 weeks to a month). During this period, sex contacts are prohibited.

I have passed a course of treatment from a disease associated with ureaplasm (mycoplasmas) and the pathogen was not determined on the control examinations. However, after a while, my symptoms of the disease appeared again and the pathogen was discovered. How can this be if during this period I did not have any sex contacts?

The most often re-identification of ureaplasma is due to the fact that there was no complete eradication (disappearance) of the pathogen and its amount after treatment decreased to the minimum that cannot determine modern methods diagnostics. Through a certain number of VRMS, the propulsion was reproduced, which was manifested by the recurrence of the disease.

I passed a quantitative analysis on ureaplasmu (mycoplasmis) and they found them in quantity (titer) less than 10x 3. My doctor says that I do not need to be treated, as the treatment is appointed at a higher titer - more than 10x3? Is it true?

The need for treatment is determined not by the amount (titer) of the detected microorganism, but the presence or absence of the disease of them called. If there are signs of the disease, you must receive treatment. It is also recommended to treatment, regardless of the identified titers with a quantitative analysis and the presence of signs of the disease, in the following cases: if your sexual partner has signs of the disease caused by ureaplasm (mycoplasmas) and (or) you are planning to change the sexual partner and (or) Pregnancy soon.

The article uses materials from reviews

Ken B Waites, MD, Director of Clinical MicrobioLogy, Professor, Department of Pathology, Division Of Laboratory Medicine, University Of Alabama At Birmingham

Description

Preparation

Indications

Interpretation of results

Description

Definition method PCR with detection in real-time mode.

The material under study Epithelial Cell Scraps Urogenital

The qualitative definition of the DNA of mycoplasma (Mycoplasma genitalium) in the scrapings of the epithelial cells of the urogenital tract, by the method of polymerase chain reaction (PCR) with detection in the "real-time" .Mycoplasma genitalium - pathogenic microorganism, causes diseases of the urinary tract. Mycoplasmas are transmitted during sexual contacts, they may cause non-flowered urethritis and prostatitis, inflammatory diseases of a small pelvis, pathology of pregnancy and fetus, infertility in women and men.

Analytical indicators:

• the defined fragment is a specific DNA section of Mycoplasma Genitalium;
• specification specificity - 100%;
• sensitivity analysis - 100 copies of Mycoplasma Genitalium DNA in the sample.

Preparation

Examination of women is advisable to conduct in the first half of the menstrual cycle, not earlier than a 5-day day. It is permissible to examine in the second half of the cycle, no later than 5 days before the alleged start of menstruation. In the presence of pronounced symptoms of inflammation, the taking of the material is carried out on the day of circulation. On the eve and on the day of examination, the patient is not recommended to dock the vagina. The taking of biomaterial is not recommended against the background of antibacterial therapy (general / local) and during MENSES, previously 24-48 hours after sexual contact, intravaginal ultrasound and colposcopy. It is recommended to take the material not earlier than 14 days after the use of antibacterial drugs and local antiseptics, and no earlier than 1 month after the use of antibiotics orally. If scraping from the urethra take to study, the collection of material is carried out before or no earlier than 2 - 3 hours after urination.

Indication for appointment

• The establishment of the etiology of the chronic infectious process of the urogenital tract.
• Straight picture of inflammation of the urogenital system.
• Pregnancy.
• Ectopic pregnancy.
• Infertility.
• Weakening immunity.
• Monitoring the effectiveness of antibiotic therapy (no earlier than a month after the reception of antibacterial drugs).
• Preventive screening studies (to exclude the likelihood of asymptomatic and latent flow infection).

Interpretation of results

The interpretation of research results contains information for the attending physician and is not a diagnosis. Information from this section cannot be used for self-diagnosis and self-treatment. The exact diagnosis is made by the doctor using both the results of this survey and the necessary information from other sources: anamnesis, the results of other surveys, etc.

Test quality. The result is issued in terms "detected" or "not detected."

• "Detected": in the analyzed sample of biological material found a DNA fragment specific to Mycoplasma Genitalium: infection of Mycoplasma Genitalium;
• "Not detected": In the analyzed sample of biological material, no DNA fragments were found specific to mycoplasma genitalium or the concentration of the pathogen in the sample below the test sensitivity boundary.

Please note that the timing of the implementation of PCR studies can be increased during confirmation tests.

5 004

Mycoplasmosis and ureaplasmosis are diseases that do not have any specific symptoms inherent in only these infections. Therefore, laboratory research methods are decisive for the diagnosis.

In order to reliably determine the diagnosis " urogenital mycoplasmosis" or " ureaplasmosis"I need 2 required conditions:

1. The presence of the inflammatory process of the urogenital system.
2. The presence of the causative agent of mycoplasma or urepalasm, proven laboratory methods. In this case, other possible pathogens must be absent.

Who, first of all, should be examined for chlamydia?

• Women and men suffering from infertility of an unknown reason for more than 2 years.
• Women with chronic inflammatory diseases of the urinary system of unclear etiology (especially when planning pregnancy).
• Pregnant women who used to have spontaneous miscarriages, premature birth, multi-way, etc.
• Pregnant women with the unfavorable course of this pregnancy.
• Patients with urolithiasis and pyelonephritis, because They are a group of high risk by mycoplasmosis.
• Patients with prostatites for long-term urethritis.
• In front of gynecological and urological operations.

Is it necessary to undergo a survey if there are no symptoms of the disease?
It is necessary only in the above cases. At the same time, there is no need to conduct special examinations on Miko- and ureaplasmosis during preparing or during pregnancy, if a woman does not bother. The fact is that in the norm, these bacteria are encountered about 50% of women, so even in the absence of complaints, they can be detected, but it is not worth treating the asymptomatic carriage of these microbes.
In all other cases, it is also no need to pass tests on Miko and Ureaplasmosis "Just in case".

What do you investigate?
To detect Miko- and ureaplasm, it is necessary to make a fence material. This may be a scraping containing the cells of the patient organ - the vagina, the cervix, the secret of the prostate, the scraping of the urethra, the conjunctiva of the eye. Such material may also be blood, urine and sperm in men.

What tests are prescribed during mycoplasmosis and ureaplasmosis?
With Miko- and ureaplasmosis, the following tests are the most appropriate:
1. Polymerase chain reaction (PCR) - determination of the DNA of the pathogen.
2. Immuno-immunimal analysis (ELISA) - definition of antibodies to the causative agent.
3. Microbiological research (culture method) - finding directly the most causative agent.

1. Polymerase chain reaction (PCR).

• The method is based on the detection of the genetic material of the pathogen in the studied sample. With the help of PCR, a specific area or a fragment of the MICO- and ureaplasm DNA is detected in the material under study, therefore, in comparison with other methods, it is impossible to confuse them with some other infection.
• PCR allows you to detect the pathogen even with hidden, chronic and asymptomatic forms of infection, when other research methods are not informative.
• With the help of PCR it is possible to discover Miko- and ureaplasm even in incubation periodWhen there are no clinical manifestations of mycoplasmosis.
• For the analysis of PCR, it takes quite a bit of material, and the results are ready after 1-2 days.
• In the diagnosis of primary infection, more informative is to identify this infection in the fields of initial localization, i.e. The material should be slosples from sex tract.
• When analyzing PCR, false positive results are possible. This may happen if the study was previously conducted than a month after the course of antibiotic therapy. The fact is that when the DNA fragment is detected, mycoplasma is impossible to evaluate whether this or viable microbial cell. In this case, the viability of mycoplasm is estimated using a microbiological method. If bacterium is not focusing, then, despite the presence of a DNA fragment, microbial cells will not grow in cell culture.
• False negative results are also possible in violation of the process of fence, transportation of material and the analysis itself.
• To date, the accuracy of this method with its proper execution is the highest - up to 100%.

If PCR analysis on mycoplasma is positive, and there is no symptoms of mycoplasmosis, it is necessary to carry out other research methods.

2. Immuno for analysis (ELISA) - definition of antibodies to the causative agent.

• IFA is the method of indirect identification of bacteria, i.e. The pathogen is not detected directly, but the specific antibodies (IgG, IgA, IgM) are determined to it and the body's response to its implementation.
• ELISA allows you to determine at what stage there is a disease - acute or chronic, and evaluate the effectiveness of the treatment.
• Specific Ig A are generated with fresh infection, Igm indicates the presence of an active infection. The presence of only IgG without IGM speaks of the infection transferred in the past, which is currently missing or carrier. For more information on the assessment of the results of the analysis of the ELISA, see article "".
• The accuracy of the ELISA is about 80%. This is due to the fact that antibodies to chlamydia may be present in healthy people as a result of the previously suffered disease, as well as determined in respiratory and other types of mycoplasma infections.

3. Microbiological research (Cultural method) With the definition of sensitivity to antibiotics.

• The essence of this method is that the material under study is sewn to a special environment and is grown. Then, the pathogen is then identified by nature and other features. The culture method allows not only to identify viable Miko and Ureaplasma, but also to choose the antibiotic to which they are sensitive.
• Diagnose mycoplasmosis is quite difficult, because Mycoplasma can be a component of natural microflora of urinary organs in healthy faces. The presence of Miko- and ureaplasm in the results of analyzes is not yet a disease. For accurate diagnostics, it is necessary to know the number of bacteria in the urinary organs.
• Only the culture method allows to determine the amount of pathogen in the material under study, which means to distinguish asymptomatic carriage of Mico- and ureaplasm from the relevant diseases. To do this, the number of colonies that grew on the medium, which call the colony-forming units (CE) is calculated. This number indicates the number of live bacteria that can multiply, forming a colony.
• With asymptomatic healthy carrier, Micro- or ureaplasm is defined less than 104 CFU / ml. In the presence of a disease, the number of colonies mycoplasm or ureaplasm in the material under study will be more than 104 CFU / ml.
• The accuracy of the detection of bacteria at the same time reaches 95%.
• Additionally, see the article "?".

So, all these 3 methods are quite accurate, but they are all complementary.
Why? To do this, it is necessary to clearly understand the possibilities of each method.

Opportunities and restrictions of laboratory tests.

• IFA: It makes it possible to estimate the state of immunity and the reaction of the body on the causative agent, indirectly indicates the presence of Miko- or ureaplasm throughout the body, but does not indicate a specific affected organ. Allows you to evaluate the effectiveness of antibiotic therapy. But with a weak immune response, for example, in patients with immunodeficiency, IFA is not informative.
• PCR: allows you to accurately determine the location of the pathogen, but it is not always available (for example, in the ovaries). Allows you to detect the pathogen even with hidden, chronic and asymptomatic forms, as well as in the incubation period. It is characterized by the highest accuracy of the identification of the pathogen. It does not allow to assess the effectiveness of antibiotic therapy, to distinguish the carriage of the disease, evaluate the viability of the pathogen.
• Cultural method: Allows you to identify viable bacteria, determine their quantity, assess the effectiveness of antibiotic therapy, to distinguish the carriage of the disease. Does not evaluate the reaction of the body on the causative agent.

conclusions

• There is no method that in 100% of cases revealed mycoplasms. therefore laboratory diagnostics Must include at least two methods.
• If it is impossible to take the material from the organ under study using ELISA.
• To assess the effectiveness of treatment, the culture method is used. If it is impossible to carry out IFA.
• To determine the stage of the disease - IFA.
• In patients with immunodeficiencies, IFA is not informative, PCR is used and the culture method.
• Do not particularly rely on the results to determine the sensitivity of mycoplasmas towards antibiotics. After all, as you know, microorganisms behave differently in the tube (in vitro) and in a living organism (in vivo).

Dna of Mycoplasma Hominis, in Scraping by PCR Qualitative Analysis

Mycoplasma Hominis is one of the types of mycoplasma, special microorganisms that occupy an intermediate stage between the simplest, viruses and bacteria. This is a conditional pathogen ...

The average price in your area: 340 from 220 ... up to 380

13 laboratories make this analysis in your region

Description of research

Preparing for research:

Scraping from the urethra. Before taking the patient, it is recommended not to urinate for 1.5-2 hours. Before taking the ma-course from the cervical canal, it is necessary to remove the vatamppon mucus.

The material under study: Scraping

DNA Mycoplasma Hominis

Method

PCR method - polymerase chain reaction that allows you to identify the presence in biological material the desired portion of the genetic material.
- Its varieties, advantages and applications in medical diagnostics.

Reference values \u200b\u200b- norm
(Mycoplasma Hominis (Mycoplasmosis), DNA (PCR), high-quality, scraping)

Information regarding reference values \u200b\u200bof indicators, as well as the composition of the indicators included in the analysis may differ somewhat depending on the laboratory!

Norm:

Research Qualitative, the result is defined as "positively" / "detected" or "negative" / "not detected."

Indications

• Suspicion of mycoplasmafe with infection, especially with a frequent change of sexual partners.
• The sluggish inflammatory diseases of the urogenital system (especially in the absence of chlamydia, gonococci, trichomonad, M. genitalium).
• Diseases of the respiratory system of unexplained etiology.
• Planning pregnancy (examination you need to go through both spouses).
• Unbearable pregnancy, infertility.
• 1 month after the end of antibacterial therapy to control its efficiency.

Improving values \u200b\u200b(positive result)

The result is "positive" / "discovered":

• Detection of DNA M. Hominis in combination with symptoms of inflammation and the absence of other pathogenic pathogens (chlamydia, gonococci, trichomonad, M. genitalium) indicates the presence of a mycoplasma infection.
• Detection of DNA M. Hominis in small quantity Without signs of pathology of the organs of the urogenital system, testifies to carriage, or mycoplasmism.

Lowering values \u200b\u200b(negative result)

The result "Negative" / "Not detected":

• The presence of an infection caused by M. Hominis is unlikely.