What does Augmentin look like. "Augmentin", suspension for children: instructions for use, dosage. Augmentin during pregnancy and lactation

Antibiotic penicillin row "Augmentin" is allowed both adults and children. It is discharged in many infections. But sometimes, young mothers are not waiting for the recommendations of the doctor or vice versa, in spite of them, replacing the "Augmenitin 400" what the doctor wrote down. In this case, problems may arise with the correct dosage of the Augmentin 400 suspension for children. In order not to harm, but to gain valid benefits from good and, in many cases, the useful drug should be understood in some subtleties.

Characteristics of the suspension "Augmentin 400"

Augmentin 400 is developed on the basis of amoxicillin - a wide spectrum antibiotic and clavulanic acid that protects amoxicillin from destruction.

Amoxicillin is the main substance of the suspension "Augmentin 400". It is he who has a bactericidal and antibacterial effect on the body. The lack of amoxicillin is that some microorganisms are addictive to it. This means that they simply cease to respond to the drug. Here in the game just enters the clavulanic acid. It makes viruses less stable.

Amoxicilline is an antibiotic of the penicillin group and therefore transferred to even young children and pregnant women, except in cases of individual intolerance.

But it must be remembered that he, like most drugs, has its own side effects. And also, it is contraindicated in the disease phenylketonuria, as well as with renal failure and liver diseases.

Suspension "Augmentin" is prescribed in various infections of the respiratory tract, skin diseases, a genitourinary system.

Helps the reception of agletin suspension and at osteomyelitis. It is an excellent prevention of infections in the case of surgical operations.

How to prepare a suspension "Augmentin" and how to take it:

The drug must be poured into a bottle and pour boiled water. Attention! Water should not be hot;
Further, it is necessary to shake it well, to maximize the granules and leave minutes to 4. During this time, even the smallest particles will be able to dissolve.
But if you see that this did not happen, then shake the bottle again and retain another 5 minutes.
Then you need to add water to the mark.
Only after that the drug can be considered ready for use.
Ready suspension can be stored in the refrigerator - up to 7 days, but do not freeze. After 7 days, it is prohibited after 7 days.

When you take out a suspension from the refrigerator, it is necessary to shake it well and cast the right amount per dim spoon. You can dial the required volume with a syringe.

Do not forget that all items that you use must be carefully handled. In no case do not allow the particles of the suspension to fall on a spoon or the syringe, and were used several times without washing.

If a child can drink a suspension, for example, because of the taste unpleasant for him, add the amount of water is allowed. But at the same time, it is necessary to drink all this solution.

Dosage of the Augmentin 400 suspension for children: instructions for independent calculation

The powdered drug "Augmentin" can be purchased in pharmacies in various versions in which amoxicillin concentration and clavulanic acid are different:

125 mg of amoxicillin + 31.35 mg of clavulanic acid;
200 mg of amoxicillin + 28.5 mg of clavulanic acid;
400 mg of amoxicillin + 57 mg of clavulanic acid.

In all embodiments, the main dosage is 5 ml of the finished suspension. But you should know that always the calculation of the dosage of Augmentin 400 occurs at amoxicillin concentration: 125, 200 or 400. This is important to understand in order to remember that these drugs do not replace one other. And if you were discharged "Augmentin 400", it cannot be replaced with "Augmenitin 200" or "Augmented 125" and vice versa.

The reception of the Augmentin 400 suspension is usually discharged by children over 12 years and adults. The baby's body weight should be more than 40 kg. But the reception of children under 2 years old is contraindicated. For them, "Augmentin 125" is suitable.

The dosage of the Augmentin 400 suspension for children is individual - it is necessary to take into account the body weight, the severity of the disease, age. The dosage is calculated only by amoxicillin.

If the drug is prescribed to a child under 12 years old, then it is necessary to monitor that 1 kilogram of body weight turned out no more than 45 mg and at least 25 mg of antibiotic.

The severity of the disease also plays a big role. For example, with skin infections, chronic tonsillite - the dose of the antibiotic is minimal. But with acute infectious diseases, pneumonia, bronchitis - common doses of the drug are increasing.

It is worth remembering that there are also the number of drug techniques. For example, a child, age under 12, it can be given only 1 or 2 p. in a day. And the break between the two techniques should be at least 12 hours.

An example of calculating the drug:

Baby 8 years, weight - 27 kg. Disease - otitis. It is necessary 45 mg of the drug per 1 kilogram of weight. This means that the overall dosage of the drug will be 1215 mg, which will be divided into 2 receptions - 607.5 mg.

In 5 ml of the suspension "Augmentin" - 400 mg, which means that 7.6 ml should be made for one reception, or 15 ml per day.

It is not very easy to calculate the accurate dosage of the suspension "Augmentin 400" for a child. So how to make some mathematical actions. Often, parents are confused in them, so there are averaged values. But it is better to use these values \u200b\u200bonly as a hint. That is, check on them, is it true calculations are made.

For example, a child from the year and weighing up to 18 kg cannot be taken more than 5 ml of the finished suspension "Augmentin". An older than 6 years old from 19 kg can already have 7.5 ready suspensions. If the child has already been 10 years old, and it weighs more than 29 kg, then it needs 10 ml of suspension for one reception. But in these values \u200b\u200bthe disease itself is not taken into account or its severity.

All analogs of Augmentina refer to one price category, the most cheap, according to the monitoring data - Rapiklav (~ 310 rubles for 500/125) and artlet (~ 280 p.)

Amoxiclav;
Artilet;
Rapiklav;
Ecoclav;

Price

The average price online *, 364 p. (Table P / O 500mg / 125mg №14)

Where can one buy:

Instructions for use

Augmentin is an antibiotic from a group of penicillins, which is active in relation to most pathogenic bacteria. The drug is widely used to treat inflammatory diseases of various organs and systems. Relatively low toxicity allows you to use it in children of younger and pregnant women after consulting with the attending physician

Structure

Augmentina includes amoxicillin antibiotic and clavulanic acid.

Amoxicillin is an antibacterial agent with a wide range of antimicrobial activity.

This substance can be collected under the action of specific enzymes of some bacteria (beta-lactamas), so amoxicillin is not active against microbes that produce beta lactamases.

To expand the antimicrobial activity of the Augmentin in its composition included clavulanic acid. This substance has the ability to suppress the production of beta-lactamas. Thanks to this combination, Augmentin works where ordinary amoxicillin does not work.

Indications

Augmentin is shown for use in diseases and conditions caused by pathogenic microorganisms that are sensitive to this antibiotic. In what situations it can be recommended to the patient:

Inflammatory diseases of the upper departments of the respiratory tract, including the pathology of LOR-organs (tonsillites, pharyngitis, laryngitis, otitis, sinusit, etc.).
Acute and exacerbations of chronic diseases of the lower respiratory tract, for example, in tracheobronchites or pneumonia of various localization.
Pathology of the urogenital system (cystitis, urethritis, etc.), including gonorrhea.
Diseases of the skin and subcutaneous fatty fiber: Furukkul, Carbuncoon, etc.
The pathology of bones and joints caused by the bacteria sensitive to this antibiotic, for example, with bacterial osteomyelitis or arthritis.
As part of comprehensive therapy in combination with antibiotics of another group for the treatment of severe mixed infections (sepsis, peritonitis, etc.).
In order to prevent postoperative infectious complications. Augmentin can be appointed to the patient to prevent complications after the operation on the heart, stomach, kidneys and other organs and tissues.

Method of application and dose

The drug is released in the form:

Tablets. Dosages: 250 mg + 125 mg (375 mg), 500 mg + 125 mg (625 mg), 875 mg + 125 mg (1000 mg), where the first digit is the amount of amoxicillin, and 125 mg is clavulanic acid.
Powder for the preparation of suspension. Applied in children. Dosage: 125 mg of amoxicillin + 31.25 mg of clavulanic acid, 200 mg + 28.5 or 400 mg + 57 mg, respectively.
Powder for preparing a solution for intravenous administration. Dosage: 1000 mg of amoxicillin + 200 mg of clavulanic acid.

Thus, the drug can be administered intravenously or the patient can drink tablet forms. Children from three months to 12 years old with a body weight of up to 40 kg, Augmentin are prescribed in the form of a suspension for receiving inside.

The dosing mode and the multiplicity of reception depends on the patient's condition, the severity of the inflammatory process, the presence of concomitant diseases and other parameters.

Dosage for adults and children after 12 years is selected individually.

With light and medium-free infections, 1 tablet 250 + 125 mg or 500 + 125 mg 3 times a day are prescribed. In severe cases, the doctor prescribes 1 tablet 875 + 125 mg 2 times a day.

Patients with severe kidney and liver disorders require dosage correction, taking into account the performance of these organs.

Contraindications

The drug is contraindicated for use in patients with allergies or individual intolerance to the antibiotics of a penicillin row or clavulanic acid.

In addition, the medicine is not prescribed to patients who, in history there were cases of jaundice or disruption of the liver when using preparations from the penicillin group.

Important! Given the similar chemical structure of penicillins and antibiotics from the cephalosporins group, this medication is greatly caution prescribed patients with allergies to cephalosporins.

In patients with severe violations of the liver and kidney function, the drug should undergo under constant control of the function of these bodies with the help of laboratory and instrumental studies.

Pregnancy and lactation

Augmentin can be used during the battery period, if the estimated benefit for the mother is higher than the possible risk for the future child.

During this period, the prescription of the drug should be strictly agreed with the doctor.

The study of the influence of this antibiotic in laboratory conditions did not reveal a negative effect on the fruit and the course of pregnancy. In single research in women, it was proved that preventive therapy with this antibiotic can increase the risk of enterocolitis (intestinal inflammation) in a child.

During breastfeeding period, the drug can be appointed nursing mom. At the same time, there is a risk of developing thrush of mucous membranes (candidiasis) or diarrhea in an infant. In the event of such negative reactions in babies, breastfeeding for the treatment stops.

Overdose

Under the overdose of drugs in patients, symptoms of the disorder of the digestive tract can be observed. In addition, there is a violation of the water-electrolyte balance, which is manifested by edema, dryness of mucous membranes and other signs.

Side effects

Based on clinical studies of the drug and observation of patients, the following possible adverse reactions were revealed after receiving augmentin:

The digestive tract: diarrhea, vomiting, nausea, meteorism and bloating, less often the sick worried abdominal pain. There are isolated cases of the development of colitis (inflammation of the large intestine), hepatitis and jaundice.
From the side of the skin: allergies in the form of itching, rash urticaria. Candidiasis of the skin and mucous membranes is found. There is a risk of developing severe allergic reactions, such as generalized urticaria or Stevens-Johnson syndrome.
Liver: moderate or insignificant increase in the level of basic hepatic enzymes.
Change of blood indicators: reducing the number of leukocytes, platelets, an increase in the number of eosinophils, etc.
Nervous system: headaches, dizziness, sleep problems. Less often in patients with severe accompanying diseases of other bodies, convulsions are observed.
Immune system: allergic vasculitis, swelling, anaphylactic shock. This type of adverse reaction is very rare.

Important! Injecting the injection of the drug, there is a risk of thrombophlebitis in the injection site.

Interesting! Additionally, the immunomodulating properties of clavulanic acid are revealed, so its presence in the antibiotic significantly expands the spectrum of activity and helps to destroy bacteria.

Pharmacology

After applied inside both components of Augmentin quickly absorbed the gastric mucosa.

After that, they can be found in therapeutic concentrations in a bile bubble, muscle tissue, in the abdominal organs and in other tissues and systems.

Important! It is better to take the drug before starting meals, then his suction will be maximal.

In the body, the antibiotic suppresses the growth and development of bacteria sensitive to it.

It is removed from the body mainly by the kidneys, to a lesser extent with the bile of the liver. Given this fact, patients with problems and diseases of these bodies need dosage correction and constant control.

Other

The medicine is released in a pharmacy according to the recipe of a doctor. The shelf life is two years.

Store tablets at a temperature not higher than 25 degrees. The finished suspension is placed in the refrigerator at a temperature of 2-8 degrees, it is necessary to use it during the week after breeding.

The article provides an overview of the drug Augmentin (children's antibiotic, a form of release - powder for preparing a suspension) in dosages 200 mg / 28.5 mg / 5 ml and 400 mg / 57 mg / 5 ml, an example of a dose of medication is given depending on the weight of the child.

Augmenitin suspension - a wide range of a wide range of action. It can be given from the first months of life.

Augmentin is an antibiotic, as part of which two active substances. First - amoxicillin, having an antibacterial effect (But its action is depressing by some types of microorganisms). To eliminate this disadvantage, it was introduced into the drug second active substance - Clawulanic acid. It destroys the protection of microorganisms, which, in its absence, are not amenable to amoxicillin.

Indications for application

Side effects

After receiving the Augmentation in children often begins due to death. To normalize the chair, let's kid something from this list:

(Three times a day on 1 jar).
(1 capsule three times a day). If a child does not know how to swallow capsules, their contents need to be poured into a spoon and mix with water.
(together with the admission of an antibiotic 15-60 drops, depending on age). When the chair is normalized, the dosage is reduced by half, and they drink anyway for 14 days.

Violation of digestion is a negative consequence after treating by the carment.

Sofia, Mom 5-year-old Gleb, told in the revocation about how to cope with the possible nausea caused by the Acceptance of Augmentin:

"In the son of his son, the doctor appointed Augmentin in suspension. But after the first reception of Gleb began to sick, as a result, it broke out. And the son is suffering, and no benefit. The next day they went to the clinic again to replace the drug. The doctor was surprised asking and asked to argue her. After listening to the complaint, he said that you can cope with nausea if you take an antibiotic strictly before meals. That is, they sat down at the table, drunk a suspension - and immediately there. After such recommendation, the Son no longer nauseous, and angina quickly passed. "

Analogs of the drug

If the pharmacy did not turn out to be augmentin, then instead you can buy analogs. Imagine their brief overview:

- Slovak drug, distinguished only by a list of excipients.
Flemoclav. - Dutch analogue, characterized by improved suction of actors. Therefore, the effectiveness of treatment with Flemoclav is higher.
Panklaw. - European-made medicine.
Rapiklav, Ranklav, Claimar - Cheap analogs can be purchased from Russian and Indian manufacturers. They are distinguished by reduced bioavailability, but a democratic price.

I will be healthy!

Augmentin is a widely used antibiotic, efficient, but sometimes causing diarrhea. Side effects can be eliminated by compliance with the rules of reception of the drug and the combination of it with bacterial therapy. And it is not necessary to go to another pharmacy for Augmentin if you found any of the analogues. According to the composition of the existing components, they are identical, only manufacturers differ.

Alisa Nikitin

Many diseases in children can not be cured without resorting to help antibiotics. Very often doctors prescribe these potent medicines. A competent parent should know how when and why the kid should take an antibacterial drug. And so that you feel easier to figure out, we have prepared for all occasions.

Wide spectrum of action. It is prescribed for diseases caused by microflora, sensitive to amoxicillin.

Biologically active components and dosage forms

The active components of the augmentin are amoxicillin (antibiotic from a group of semi-synthetic penicillins) and clavulanic acid (beta-lactamase inhibitor).

The medicine is produced in tablet form and in the form of powder. The composition of 1 tablets includes 250, 500 or 875 mg of amoxicillin trihydrate and 125 mg of potassium salts of clavulanic acid.

5 ml of suspension, which is obtained during powder dilution, contains 125, 200 or 400 mg of amoxicillin and 31.25, 28.5 or 57 mg of clavulanic acid salts, respectively.

Tablets are supplied in blisters (7 or 10 pcs.).

Indications

Augmentin is prescribed in infectious diseases caused by some species, hemophilic chopstick, moraxellas, echryochia () and gonococci.

The drug is prescribed under the following pathologies:

The sensitivity of pathogenic microflora to penicillins can vary, therefore it is advisable to pre-conduct crops and laboratory tests with an antibiotic.

Who can not be taken by Augmentin?

The absolute contraindication to the use of augmentin is hypersensitivity to active substances of tablets and suspension, as well as increased sensitivity to other β-lactams, including cephalosporins and penicillins.

The drug is contraindicated with diagnosed, and also if the patient had episodes of hepatic dysfunction or jaundice against the background of taking agothetin or drugs with the same active ingredients.

note

Tableled forms do not give children and adolescents up to 12 years (or with body weight< 40 кг). Суспензия разрешена к применению с 3-месячного возраста.

Diagram of reception and optimal doses

Augmentin takes continuous courses, the minimum duration of which is 5 days. Therapy for more than 2 weeks in a row is only after an objective assessment by the attending physician of the clinical picture and the dynamics of the process.

The usual dosage for patients from 12 years and older with a relatively easy course of infection is 250 mg of amoxicillin 3 times a day. With a complicated process, a 500 mg reception is shown 3 times a day or 875 mg 2 times.

1 tab. 875 mg corresponds to 11 ml of suspension.

2 tab. 250/125 mg are not equivalent to 1 tab. 500/125 mg.

To obtain a suspension to powder, 60 ml of water is added. The bottle with the liquid needs to be shaped until the drug is completely dissolved, after which it is to withstand 5 minutes, to add water to special risks and shake again.

note

The finished liquid can be kept in the refrigerator no longer than 1 week. Do not allow freezing to avoid inactivation of the drug!

For children from 3 months. Up to 12 years old, the average daily dosage is determined at the rate of 30 mg of amoxicillin per 1 kg of weight. High doses are 40-45 mg, and low - 20-25 mg / kg of weight.

Low dosages are effective in infectious dermatitis and inflammation of almonds, and high prescribed during otitis, inflammation of the apparent nasal sinuses, infectious diseases of the urogenital system and osteomyelitis.

A suspension of 125 mg / 5 ml gives children three times a day with 8-hour intervals, and a solution with an amoxicilline content of 200 or 400 mg per 5 ml - 2 times a day, withstanding 12-hour time intervals.

Side effects

In individual hypersensitivity to active substances, anaphyactic reactions are possible, which for the patient can end fatly.

By the number of side effects include:

fucking problems;
dyspeptic disorders;
itching and rash on the skin.

Overdose

With a significant excess of age dosages, disorders of digestion and violation of water-salt equilibrium are possible. The development of the functional deficiency of the kidneys is also not excluded.

Overdose shows the purification of the stomach and symptomatic therapy. In difficult situations, it may be necessary to hospitalize the victim and the conduct of hardware purification of blood - hemodialysis.

note

Doses within 250 mg / kg of weight do not cause serious disorders in children.

Augmentin's interaction with other LS

Plasma antibiotic concentration increases against the background of the reception Samplecid. With a combination of S. Allopurinol Risk of skin allergic reactions increases.

Augmentin increases overall toxicity methotrexat Due to the slowdown in its excretion.

Antibiotic is able to reduce efficiency oralBecause violates their absorption.

Additionally

Special caution must be observed patients with a decrease in the functional activity of the liver.

Prolonged antibiotic therapy leads to And the reproduction of strains of insensitive to beta lactams of microflora.

It is advisable to take tablets during meals to reduce the likelihood of the unwanted effects of components on the organs of the digestive tract.

At the time of course therapy, it is advisable to refrain from the management of vehicles and work with other potentially hazardous mechanisms, since one of the possible side effects is dizziness.

During treatment, it is forbidden to take alcohol and therapeutic alcohol tinctures.

Augmentin during pregnancy

It has been established that there is a small risk of necrotizing enterocolitis in newborns, whose mothers took this antibiotic . Augmentina's use during the nesting period of the baby is allowed only by strict medical testimony..

During the lactation, the reception of the drug is allowed, since in milk amoxicillin is detected only in minimal (trace) volumes.

pharmachologic effect

Amoxicillin exhibits high activity against many representatives of pathogenic and conditionally pathogenic microflora. Clawulanic acid is inactivating β-lactamase produced by bacteria, capable of destroying antibiotic molecules.

After receiving inside the current components are absorbed in the digestive tract very quickly and almost in full. They are evenly distributed in the tissues and have a systematic effect on foci of infection. About 25% amoxicillin and slightly less than 20% of clawulanic acid salts are conjugated with serum proteins. Battery and deposit for the components of the Augmentina are uncharacteristic. Biotheraformation occurs in the liver, and unchanged substances, their conjuncts and metabolites are excreted with bile.

Refers the drug "Augmentin". Reviews This medicine has from patients suffering from various diseases.

The reason for this was the fact that the drug has in its composition two active substances that have a destructive effect on gram-positive and gram-negative microorganisms.

The effect of the drug

The drug includes two active active ingredients - a semi-synthetic amoxicillin antibiotic and clavulanic acid. Amoxicillin, penetrating the body, stops the formation of new microbes. This is due to the destruction of the protein, which is necessary for the vital activity of microorganisms. Clawulanic acid helps to preserve the action of penicillin. A drug is produced in the UK.

Indications for the use of drug "Augmentin"

The drug is prescribed in the occurrence of infectious inflammatory diseases caused by microorganisms sensitive to the drug. The list of such diseases is wide:

To prevent the development of infectious diseases after a different kind of operations, the drug "Augmentin" is also prescribed. Reviews of doctors at the same time, mostly positive.

Contraindications for the use of the drug

The main contraindication to the use of the drug is the increased sensitivity to its components or their intolerance. Violation of the functions of the liver is another reason to refuse to use it.

Side effects of antibiotic

Doctors appointed by their patients antibiotic "Augmentin", reviews of patients about the drug analyze, study, make appropriate conclusions. As a result of this work, a list of possible side effects of medication on the human body appeared. Such phenomena may concern the gastrointestinal tract (nausea, diarrhea, vomiting). It is very rare the manifestation of allergic reactions in the form of urticaria, quinque swelling, dermatitis. Other forms of allergies are possible. There are isolated cases of violation of the liver, the development of colitis and other serious diseases. All these circumstances suggest that the drug is strictly contraindicated with the drug. The observation of the doctor is a prerequisite for the reception of the drug "Augmentin".

Forms of release of drug

The Augmentin medication is available in 1000 mg tablets, 625 mg, 375 mg. In addition, the drug may be in powder vials. The doctor, prescribing the medicine, usually gives detailed recommendations. There is a powder from which the syrup is prepared to receive inside. In the vial poured warm boiled water to the desired mark, the means are well, after which it is fully prepared for use. Other bottles contain powder from which a solution for intravenous injections is manufactured.

Drug use method

The drug "Augmentin" can be appointed both adults and children. Dosage medication, the form of its reception depend on the age of the patient and the severity of the disease. Adult patients and children over 12 years old are usually prescribed tablets of different dosages. And for the kids of younger age, the drug "Augmentin" in the form of a syrup is intended. Its dosage and reception frequency are regulated by a doctor. The duration of reception of the drug is most often a week. With a serious course of the disease, the doctor can extend the period of receiving medication and increase its dose.

The first and most important advice sounds like this: take only the appointment of the doctor an antibiotic "Augmentin"! Reviews The drug has positive, but this does not mean that it is completely safe, and it can be used unreasonable. The drug "Augmentin" refers to the antibiotics of choice. It is prescribed frequently ill children with the ineffectiveness of other drugs of this group. To avoid the appearance of side effects, it is necessary to comply with all instructions and precautions in the treatment of means. For example, his reception will serve as a better absorption during meals. Compliance with this rule will make rid of the occurrence of side effects. It is recommended a tablet of the drug under consideration. Be sure to drink a large amount of fluid. Abundant drink is strongly recommended not only at the time of reception of the drug, but during the entire course of treatment with this means. Some experts do not advise the medication to people with reduced immunity. But the protracted form of the disease will require for complete recovery of the mandatory intake of antibiotics. Doctors pay attention to patients on the fact that the occurrence of side effects is allowed, but they do not have complications. The use of the drug pregnant women is not contraindicated, but its reception in the first 12 weeks requires caution. Special studies conducted on animals have shown that the use of medicines when entering the child does not cause a negative impact on the development of the fetus. Clinical studies did not reveal the toxicity of the medication, its influence on the reproductive function of a woman. Doctors warn patients that the simultaneous use of the drug "Augmentin" and another drug-based drug must be coordinated with a specialist. In some cases, the combination of drugs may cause severe side effects. During long-term treatment with an antibiotic, a periodic blood test is necessary. Its result may indicate the effectiveness of treatment, the safety of the drug, the ability to assign an additional course of therapy or its full replacement.